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Table 1 Curcumin neutralizes αS-induced cytotoxicity in SH-SY5Y cells

From: Curcumin reduces α-synuclein induced cytotoxicity in Parkinson's disease cell model

Sample LDH (% control) SE p-value Viability (% control) SE p-value
Tris buffer (control) 100 2.4 NA 100 4.3 NA
αS 121.5 3.5 0.005a 67.9 1.9 0.004a
αS + curcumin 99.7 5.3 0.018b 89.1 4.1 0.008b
Curcumin 99.3 4.9 0.936 96.8 5.6 0.501
  1. Cytotoxicity was measured using LDH assay and cell viability was determined using resazurin reduction assay. SH-SY5Y cells were incubated with Tris buffer (control), αS, αS+curcumin and curcumin for 48 hr before analysis. The LDH release and cell viability were expressed as a percentage of the untreated samples. Data was reported as mean ± SE, n = 4. acompared with the control; bcompared with αS-treated samples.