Mouse brain expression patterns of Spg7, Afg3l1, and Afg3l2 transcripts, encoding for the mitochondrial m-AAA protease

Table 1 Expression patterns of m-AAA genes in mouse brain.

	Spg7	Afg3l1	Afg3l2
Olfactory bulb
Glomerular layer	+	++	+
Mitral cell layer	++	+++	+++
Granular cell layer	+/-	+/-	+/-
Hippocampus
Dentate gyrus	++	++	+++
Hilus interneurons	+	+	+++
Pyramidal layer	++	++	+++
Subiculum	++	++	++
Stratum radiatum interneurons	+	+/-	+++
Stratum oriens interneurons	+	+/-	+++
Stratum Lac-Mol interneurons	+	+/-	++
Neocortex
L 1	+/-	+/-	++
L 2	++	++	++
L 3	++	++	++
L 4	++	++	++
L 5	++	++/+++	+++
L 6	++	++	++
Striatum	+	+	+
Thalamus	++	++	++
Cerebellum
Purkinje cells	+++	+++	+++
Molecular layer	-	-	-
Granules	+	++	+
Golgi cells	+++	+++	+++
DCN	+++	++	+++
Brainstem
Vestibular n.	++	++	++
Pontine n.	-	++	++/+++
Motoneurons of III, V and VII n.	+++	+++	+++
Cuneate n./Gracile n.	++	++	+

Intensity of labeling of in-situ hybridization: - indicates absence of labeled structures; + mild labeling; ++ moderate labeling; +++ intense labeling. The scoring was relative to the highest intensity of each probe, so that the levels can be compared only within each gene but not between the three genes analyzed.

ISSN: 1471-2202