Figure 1

CreERT2 cellular sub-localization in DCX-expressing cells. a) Immunodetection showing subcellular localization of CreERT2 (green) within DCX-expressing cells (red) in the cortex of an E15.5 embryo injected with TAM at E14.5. b to e) Cre subcellular localization detected in the adult DCX-CreERT2 mice injected daily for 5 days with TAM. Immunodetection of CreERT2 (green) in the DG (b) 1 day and (c) 7 days after the last TAM injection in DCX-expressing cells (red). Immunodetection of CreERT2 (green) in the (d) OB and (e) SVZ 14 days after the last TAM injection in DCX-expressing cells (red). Insets show higher magnification of the selected areas. Scale bar in (a) = 33 μm