Figure 8
Influence of ATX and DH-ATX on the stimulation of sodium influx in cells expressing rNa v 1.2 (a, b), rNa v 1.4 (d, e) and rNa v 1.5 (g, h) α-subunits. Time-response relationships for ATX and DH-ATX-induced sodium influx in cells expressing rNav1.2 (a, b), rNav1.4 (d, e) and rNav1.5 (g, h) α-subunits; Concentration-response relationships for ATX and DH-ATX-induced sodium influx in cells expressing Nav1.2 (c), rNav1.4 (f) and rNav1.5 α-subunits (i). Each data point represents mean ± SEM from two different cultures performed in triplicate.