Figure 3
From: Viable mouse gene ablations that robustly alter brain Aβ levels are rare
Aβ levels in left and right brain halves of selected KO strains. Panel A - Median values of Aβ40 in right brain halves were plotted against median values in left brain halves. An ellipse highlights the results for UBE2R2 and ADRM1. The results for the PIGZ KO and the QPRT KO are indicated by arrows. Panel B - Same as panel A, except that mean Aβ values were plotted. Panel C - Relative values of Aβ40 and Aβ42 from left and right brain halves in individual animals is shown for four named KO strains. Note that left and right are not directly comparable because different extraction and assays procedures were used (see Methods). Bars represent the mean value.