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Figure 3 | BMC Neuroscience

Figure 3

From: Transplanted bone marrow stem cells relocate to infarct penumbra and co-express endogenous proliferative and immature neuronal markers in a mouse model of ischemic cerebral stroke

Figure 3

Identification of PKH26-labeled cells with proliferating cell nuclear antigen and doublecortin after transplantation. Colocalization of PKH26-labeled bone marrow cells with proliferating cell nuclear antigen (PCNA) (A-D) and doublecortin (DCX) (E-G) around the infarct penumbra 7 and 14 days following transplantation. PKH26 and PCNA double-labeled cells are small and occur in pair or small cluster (C, D). PKH26 and DCX double-labeled cells have round or oval somata with visible neuronal processes. PKH26 fluorescence appears weaker in these double-labeled cells relative to those seen at 7 days post cell transplantation. Scale bar (in B) = 200 μm for A, B and 50 μm for C-G.

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BMC Neuroscience

ISSN: 1471-2202

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