Figure 6From: Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesismiRNA expression is negatively correlated with target mRNA expression. Predicted target mRNAs for each miRNA were identified using TargetScan 4.0 and compared with the lists of experimentally-determined, differentially-regulated mRNAs. A two-tailed Fisher's Exact Test was used to determine whether there were more predicted target mRNAs with differential expression than would be expected by chance (p < 0.05, above heavy black line at 4.3). The negative log of the p-value is plotted on the x-axis for both down-regulated mRNAs (grey) and up-regulated mRNAs (black).Back to article page