Figure 4

Behavioural Assessments. Rats were trained on the rotorod and behavioural testing was carried out. A) Rats were placed on a moving rotorod and the time spent by the rats walking backwards on the rotorod was monitored. Measurements were made before (pre-injection), during (mid-injection) and after (post-injections) the PQ-injections. The data points represent the mean proportion of time spent walking backwards during each testing session B). Representative image of the tracking format used for determining forward/backward walking posture as well as the location of nose on the rotorod. The horizontal line is positioned at the top of the rotorod and the two vertical lines determine the forward and backward walking positions. Any nose locations between the left and right vertical lines were not counted.