Robustness of structural self-organization. Temporal evolution of clustering and closeness of structural (black) and functional (blue) networks. (A) Evolution under spatial constraints (nodes are placed randomly on a three-dimensional sphere). (B) Evolution from an initial lattice structural topology. (C) Evolution under memory guided rewiring. Insets show initial structural connectivity matrices. Compared to Figure 3, the onset of a small-world topology is faster in (B) and (C) (note the difference in time scale). Metrics derived from surrogate random networks (solid lines) are plotted for comparison. Error bars represent the standard error of the mean, as estimated over 20 simulations.