Interdependent evolution of structural and functional networks. Concurrent evolution of clustering (A), closeness (B) and modularity (C) of structural (black) and functional (blue) networks. Metrics derived from surrogate random networks (solid lines) are plotted for comparison. (D) Median, minimum and maximum rewiring rates at each rewiring step. While some nodes cease rewiring at the asymptotic state, others remain highly rewirable – hence rewiring is ongoing despite a stable structural topology. Error bars represent the standard error of the mean, as estimated over 20 simulations.