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Table 4 Average Cramér-Rao lower bounds (CRLB) of measured metabolites (± SD).

From: In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment

Mice type Brain region Gln Glu Tau m-Ins tCho tNAA
tg ctx/hipp 33 ± 8% 11 ± 2% 21 ± 7% 16 ± 3% 13 ± 3% 9 ± 2%
tg str 23 ± 6% 11 ± 4% 11 ± 2% 9 ± 2% 6 ± 1% 8 ± 1%
wt ctx/hipp 32 ± 8% 9 ± 1% 15 ± 3% 12 ± 2% 9 ± 1% 7 ± 1%
wt str 20 ± 5% 9 ± 1% 9 ± 1% 7 ± 1% 5 ± 1% 7 ± 1%
  1. Abbreviations: Gln = Glutamine, Glu = Glutamate, Tau = Taurine, m-Ins = Myo-inositol, tCho = Choline-containing compounds, tNAA = N-acetylaspartate+N-acetylaspartylglutamate, wt = wild type mice, tg = APP/PS1 transgenic mice, ctx/hipp = parietal cortex/hippocampus, str = striatum, SD = standard deviation.