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Figure 7 | BMC Neuroscience

Figure 7

From: Proteomic and functional analysis of NCS-1 binding proteins reveals novel signaling pathways required for inner ear development in zebrafish

Figure 7

Proposed model for functional interaction between Ncs-1a, Pi4kβ, and Arf1 in trafficking and secretion. Dan, Bmp4, and HA are secreted molecules that contribute to proper semicircular canal development and are predicted to require the action of an Ncs-1/Pi4kb/Arf1 signaling pathway for their secretion. Bold arrows indicate activation, whereas the bold T indicates inhibition, of this signaling pathway. Thin arrows indicate directional flow of vesicles or proteins.

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BMC Neuroscience

ISSN: 1471-2202

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