Skip to main content
Figure 9 | BMC Neuroscience

Figure 9

From: A novel role of dendritic gap junction and mechanisms underlying its interaction with thalamocortical conductance in fast spiking inhibitory neurons

Figure 9

Mechanisms of interaction of transient EPJP and EPSPs: I cap . In all panels, FS0 and FS1 are coupled by GJs (gGJ = 0.2 nS). A1) A weak, subthreshold TC input in FS0 (gray trace) precedes (6 ms) a strong, suprathreshold TC inputs to FS1 (black trace). A2) INa (gray) and Icap (black) in soma of FS 0. B1) The weak TC input arriving at FS0 precedes the suprathreshod TC inputs by 5 ms. Note that the same TC input now induced suprathreshold responses in FS0. B2) INa(gray) and Icap (black) in soma of FS 0. Note that the peak of Icap precedes the large inward INa. C) Experimental conditions in C are exactly the same with B, except that the capacitance of the FS0 was doubled. Now the same TC response failed to induce action potential in cell FS0. Note that the Icap in C2 was relatively smaller than B2.

Back to article page