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Table 3 The comparison of biological indexes in pre and post-test (Time effects) and between three groups (Time x Group interaction effects) (mean ± SD)

From: Resistance training modifies of serum levels of matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases in multiple sclerosis women - a randomized controlled trail

Variables

Time

HCON (n = 15)

(mean ± SD)

MS (n = 13)

(mean ± SD)

MS + RT(n = 12)

(mean ± SD)

Time effects

p-value

Interaction effect (Time x Group)

P-value

MMP2 (ng/ml)

Pre

Post

Pre-post P value

2.23 ± 0.95

2.19 ± 0.88

P = 0.776

6.24 ± 5.42

17.75 ± 6.02

P < 0.001

7.11 ± 1.15

6.35 ± 0.68

P < 0.05

P < 0.001,

Eta-squared = 0.385

$P < 0.001

Eta-squared = 0.605

TIMP2 (ng/ml)

Pre

Pos

Pre-post P value

0.69 ± 0.25

0.72 ± 0.23

P = 0.567

5.00 ± 1.49

4.92 ± 1.77

P = 0.632

6.10 ± 2.26

6.99 ± 2.31

P < 0.05

P < 0.05,

Eta-squared = 0.110

P ≤ 0.01

Eta-squared = 0.225

MMP-9 (ng/ml)

Pre

Post

Pre-post P value

19.47 ± 7.60

18.45 ± 7.09

P = 0.067

87.18 ± 28.56

84.09 ± 24.26

P = 0.599

59.41 ± 24.35

54.07 ± 28.26

P = 0.108

P = 0.091,

Eta-squared = 0.075

P = 0.560

Eta-squared = 0.031

TIMP-1 (pg/ml)

Pre

Post

Pre-post P value

21.93 ± 9.63

24.27 ± 10.50

P < 0.05

101.08 ± 26.06

104.75 ± 23.13

P = 0.231

94.36 ± 25.82

100.55 ± 23.32

P = 0.128

P < 0.05,

Eta-squared:0.163

P = 0.580

Eta-squared = 0.029

MMP-2/TIMP-2

(Ratio)

Pre

Post

Pre-post P value

3.66 ± 1.80

3.33 ± 1.61

P = 0.261

1.20 ± 0.81

4.08 ± 2.57

P < 0.01

1.37 ± 0.68

1.02 ± 0.41

P < 0.05

P < 0.05,

Eta-squared:0.153

P < 0.001

Eta-squared = 0.435

MMP-9/TIMP-1

(Ratio)

Pre

Post

Pre-post P value

0.97 ± 0.38

0.82 ± 0.30

P < 0.05

0.89 ± 0.31

0.82 ± 0.19

P = 0.254

0.67 ± 0.33

0.56 ± 0.33

P = 0.061

P < 0.01,

Eta-squared:0.244

P = 0.565

Eta-squared = 0.030

S100B (ng/ml)

Pre

Post

Pre-post P value

0.1136 ± 0.0045

0.1135 ± 0.0042

P = 0842

0.1479 ± 0.0157

0.1485 ± 0.0179

P = 0.721

0.1420 ± 0.0096

0.1393 ± 0.0138

P = 0.332

P = 0.445

Eta-squared:0.016

P = 0.371

Eta-squared = 0.052

  1. HCON: Health group; MS: Multiple Sclerosis; MS + RT: Multiple Sclerosis + resistance training group; MMP-2: Matrix metalloproteinases-2; TIMP-2: Tissue inhibitors of metalloproteinase-2; MMP-9: Matrix metalloproteinases-9; TIMP-1: Tissue inhibitors of metalloproteinase-9; MMP-2/TIMP-2 ratio: Matrix metalloproteinases-2/ Tissue inhibitors of metalloproteinase 2 ratio; MMP-9/TIMP-1 ratio: Matrix metalloproteinases-9/ Tissue inhibitors of metalloproteinase 1 ratio; S100B: S100 calcium-binding protein B