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Table 4 The effect of early mobilisation on BDNF

From: The effect of early mobilisation (< 14 days) on pathophysiological and functional outcomes in animals with induced spinal cord injury: a systematic review with meta-analysis

Study

Spinal segment examined

Unit of measure

BDNF

  

Intervention

Control

Cote 2011

T10-T11

Density

(ratio to control)

1

 

T12-L1

1

 

L2-L3

1.25–2*

 

L4-L6

 

1.5*

 

Macias 2009

L3-4

Density of BDNF IR fibres

30

15

Marques 2018 (a)

(b)

T8-T10

BDNF expression (relative to control %)

125%

200%

 

Sandrow-Feinberg 2009

C4 (C3 & C5)

Ratio to control

7

 

Wang 2015

L5-S1

BDNF immunoreactivity

1.5*

 

Zhan 2023 (a)

(b)

(c)

C5

Western blot technique expressed as relative to protein expression

0.75

1.25

1.25

0.5

0.5

0.5

  1. *Statistically significant. BDNF (Brain-derived neurotrophic factor)