Fig. 1

Comparison of auditory brainstem responses between Nrxn1α KO Sprague Dawley and wild-type littermates rats. ABR waveforms across different stimulus intensities (90, 70, 50 dB) under A isoflurane, B ketamine/xylazine and C medetomidine anesthesia. Recordings from the WT are in blue (N = 12) and Nrxn1α KO in red (N = 12). Data displayed as mean ± SEM, was tested with unpaired CBPT. No robust significant differences were found between genotypes across anesthesia methods. Grey bars above the graphs indicate clusters of significant differences before CBPT-based correction for multiple comparisons, i.e., indicating statistical trends