Table 2 Neurological severity scores of Mice
Task | Description | Points (success/failure) |
|---|---|---|
Exit circle | Ability and initiative to exit a circle of 30 cm diameter within 3 min | 0/1 |
Mono/hemiparesis | Paresis of upper and/or lower limb of the contralateral side | 0/1 |
Straight walk | Alterness,initiative and motor abilify to walk straight | 0/1 |
Startle reflex | Innate reflex (bounce in response to a loud hand clap) | 0/1 |
Seeking behavior | Physiological behavior as a sign of “interest” in the environment | 0/1 |
Beam balancing | Ability to balance on a beam of 7 mm width for at least 10s | 0/1 |
Round stick balancing | Ability to balance on a round stick of 5 mm diameter for at least 10s | 0/1 |
Beam walk:3 cm | Ability to cross a 30-cm long beam of 3 cm width | 0/1 |
Beam walk:2 cm | Same task but with increased difficulty on a 2-cm wide beam | 0/1 |
Beam walk:1 cm | Sanie task but with increased difficulty on a 1-cm wide beam | 0/1 |
Maximal 5 core | 10 |