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Fig. 1 | BMC Neuroscience

Fig. 1

From: Sex differences in response to obesity and caloric restriction on cognition and hippocampal measures of autophagic-lysosomal transcripts and signaling pathways

Fig. 1

Peripheral Measures. A There was a significant interaction (F1,32 = 14.21, p = 0.0007) whereby Obese females gained significantly more weight than Control females. CR reduced body weight regardless of diet. B In males, there were significant main effects for diet (F1,34 = 486.5, p < 0.0001) and treatment (F1,34 = 95.8, p < 0.0001) where Obesity increased body weight, an effect attenuated by CR. C There was a significant interaction (F1,32 = 6.8, p = 0.014) in female fasting glucose. CR reduced fasting glucose in Control females only. D There was a significant interaction (F1,34 = 14.7, p = 0.0005). CR reduced fasting glucose in Control males only. α indicates significant effect due to diet (Control vs. Obese), β indicates significant effect due to treatment (No treatment vs. CR). All significance indicators represent a p-value of less than 0.05 unless otherwise indicated

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