Table 5 Partial correlation analysis between cognitive tests and disease activity (SLEDAI), biomarkers (S100ß, IL-6, MDA, MPO, GSHr) and corticosteroid use in the SLE group, adjusted for age, education and disease duration
Cognitive tests | Cognitive domain | S100B | IL-6 | MDA | MPO | GSHr | SLEDAI | Corticoid use | |
|---|---|---|---|---|---|---|---|---|---|
RAVLT B | Verbal memory | 0.028(0.875) | 0.316(0.065) | 0.016(0.929) | 0.211(0.225) | 0.390(0.021) Better performance | 0.027(0.878) | -0.491(0.003) Poor performance | |
RCF copy | Visual constructive ability | 0.005(0.979) | -0.103(0.555) | 0.174(0.317) | -0.028(0.873) | 0.0(0.998) | -0.099(0.570) | -0.361(0.033) Poor performance | |
ST points | Inhibitory control and selective attention | -0.047(0.789) | 0.045(0.799) | -0.136(0.437) | 0.042(0.813) | 0.0(0.999) | 0.354(0.037) Poor performance | 0.023(0.894) | |
ST words | Inhibitory control and selective attention | -0.011(0.951) | 0.365(0.031) Poor performance | -0.131(0.452) | -0.043(0.806) | 0.035(0.843) | 0.224(0.195) | 0.063(0.721) | |
ST colors | Inhibitory control and selective attention | -0.214(0.218) | 0.142(0.417) | -0.268(0.120) | -0.093(0.595) | 0.024(0.890) | 0.173(0.321) | 0.339(0.047) Poor performance | |
Matrix reasoning | Reasoning | -0.199(0.253) | -0.206(0.236) | 0.176(0.313) | -0.350(0.039) Poor performance | 0.069(0.695) | 0.156(0.371) | -0.272(0.113) | |
CTT1 | Attention Processing speed | -0.069(0.694) | 0.319(0.062) | -0.425(0.011) Better performance | -0.166(0.340) | -0.047(0.787) | 0.159(0.362) | 0.234(0.177) | |