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Table 4 Association analysis between cognitive deficits (CD) and possible biomarkers in the SLE, RA and Control groups

From: Cognitive dysfunction in systemic lupus erythematosus is associated with disease activity and oxidative stress: a comparative study with rheumatoid arthritis for identifying biomarkers

  

SLE

  

RA

  

Controls

 
 

With

CD

Without

CD

p value

With

CD

Without

CD

p value

With

CD

Without

CD

p value

IL-6

579 ± 153

475 ± 249

0.064

603 ± 173

431 ± 162

0.032

562 ± 524

633 ± 434

0.427

S100B

334 ± 290

472 ± 514

0.935

474 ± 681

653 ± 1,351

0.882

809 ± 1,563

529 ± 1,065

0.637

MDA

4.78 ± 2.49

5.70 ± 8.50

0.362

7.2 ± 8.1

7.3 ± 2.7

0.115

7.0 ± 3.0

6.2 ± 5.8

0.162

MPO

15 ± 22

16 ± 16

0.497

6 ± 6

17 ± 20

0.468

3.9 ± 5.1

6.0 ± 6.7

0.584

GSHr

69 ± 49

112 ± 81

0.030

89 ± 82

98 ± 116

0.730

83 ± 64

75 ± 61

0.720

  1. CD: Cognitive deficits
  2. Data expressed in Median ± Standard Deviation. p value based on Fisher’s exact test. Statistically significant p-values ​​are highlighted in bold
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BMC Neuroscience

ISSN: 1471-2202

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