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Fig. 8 | BMC Neuroscience

Fig. 8

From: Transcriptome analysis reveals the neuroprotective effect of Dlg4 against fastigial nucleus stimulation-induced ischemia/reperfusion injury in rats

Fig. 8

APA event analysis of Dlg4. A Mapping of the APA locus of the Dlg4 gene. B APA event map of the Dlg4 gene in various brain tissues. C Ischemic PDUI and death degree of Dlg4 gene Hardy score in different periods. D Distribution of positive and negative correlation genes of Dlg4 gene PDUI-related gene expression. E The PDUI of Dlg4 was positively correlated with the expression of the anti-apoptotic gene TP53RK, and negatively correlated with the expression of the apoptosis factor TNFRSF25. The percentage of distal poly-A site usage index (PDUI) was defined as the proportion of transcripts with distal poly-A sites (used to quantify APA events). Significant correlations between gene expression levels and APA use were defined as |Rs| > 0.3 and |FDR| < 0.05

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BMC Neuroscience

ISSN: 1471-2202

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