CPHIV | HIV- | t/χ2 | p | ||||||
---|---|---|---|---|---|---|---|---|---|
Age: 5 years (N = 82) | |||||||||
Sample size (N) | 52 | 30 | |||||||
Age at scan (years) | 5.39 ± 0.31 | 5.60 ± 0.43 | − 2.64 | 0.01 | |||||
Number of males (% males) | 21 (40%) | 16 (53%) | 1.37 | 0.24 | |||||
Birth weight (g) | 3125 ± 386 | 2973 ± 603 | 1.47 | 0.14 | |||||
Estimated total intracranial volume (ETIV) (cm3) | 1375 ± 96 | 1363 ± 110 | 0.53 | 0.60 | |||||
Neuropsychological measures GMDSa | All CPHIV | IntART (n = 24) | ConART (n = 28) | All HIV- | CHEU (n = 17) | CHU (n = 13) | |||
Performance (EQ) | 74 ± 10 | 73 ± 11 | 76 ± 10 | 76 ± 18 | 73 ± 20 | 79 ± 17 | − 0.55 | 0.58 | |
Practical reasoning (FQ) | 77 ± 8 | 76 ± 10 | 77 ± 7 | 76 ± 11 | 73 ± 12 | 79 ± 7 | 0.60 | 0.55 | |
Sub-scales aggregate (GQ) | 83 ± 6 | 83 ± 7 | 83 ± 6 | 83 ± 8 | 82 ± 10 | 84 ± 6 | 0.23 | 0.82 | |
Age: 7 years (N = 125) | |||||||||
Sample size (N) | 71 | 54 | |||||||
Age at scan (years) | 7.20 ± 0.13 | 7.24 ± 0.13 | − 1.40 | 0.16 | |||||
Number of males (% males) | 36 (51%) | 30 (56%) | 0.13 | 0.72 | |||||
Birth weight (g) | 3081 ± 454 | 3081 ± 481 | − 0.01 | 0.99 | |||||
Estimated total intracranial volume (ETIV) (cm3) | 1419 ± 101 | 1444 ± 137 | − 1.17 | 0.24 | |||||
Neuropsychological measures KABCb COMPOSITE SCORES | All CPHIV | IntART (n = 32) | ConART (n = 39) | All HIV- | CHEU (n = 23) | CHU (n = 31) | |||
Mental processing index | 72 ± 8 | 72 ± 8 | 73 ± 8 | 75 ± 10 | 74 ± 10 | 76 ± 11 | − 1.90 | 0.06 | |
Non-verbal index | 74 ± 11 | 73 ± 11 | 75 ± 11 | 76 ± 12 | 73 ± 12 | 78 ± 11 | − 0.96 | 0.34 | |
Age: 9 years (N = 41) | |||||||||
Sample size (N) | 12 | 29 | |||||||
Age at scan (years) | 9.13 ± 0.27 | 9.03 ± 0.56 | 0.58 | 0.57 | |||||
Number of males (% males) | 7 (58%) | 16 (55%) | < 0.001 | 1.00 | |||||
Birth weight (g) | 3126 ± 479 | 3171 ± 466 | − 0.28 | 0.78 | |||||
Estimated total intracranial volume (ETIV) (cm3) | 1422 ± 683 | 1437 ± 135 | − 0.38 | 0.71 | |||||
Neuropsychological measures KABCb COMPOSITE SCORES | All CPHIV | IntART (n = 8) | ConART (n = 4) | All HIV- | CHEU (n = 17) | CHU (n = 12) | |||
Mental processing index | 73 ± 10 | 73 ± 10 | 72 ± 10 | 79 ± 12 | 77 ± 12 | 81 ± 12 | − 1.49 | 0.14 | |
Non-verbal index | 78 ± 10 | 78 ± 8 | 77 ± 15 | 80 ± 14 | 80 ± 14 | 80 ± 13 | − 0.46 | 0.65 |