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Fig. 7 | BMC Neuroscience

Fig. 7

From: Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner

Fig. 7

Positive effects of H2 on BBB-related protein expression in LPS-treated bEnd.3 cells cultured with GW6471- or DMSO-added medium. (A) The expression levels of PPARα, P-gp, MRP2, BCRP, VE-cadherin and occludin were detected by western blotting. Quantitative analysis of (B) PPARα/GAPDH, (C) P-gp/GAPDH, (D) MRP2/GAPDH, (E) BCRP/GAPDH, (F) VE-cadherin/GAPDH, and (G) occludin/GAPDH is represented as the percentage change in the protein level compared to control levels. n = 6 samples per group, *P < 0.05 vs. control group; #P < 0.05 vs. LPS group; &P < 0.05 vs. LPS + H2 group

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BMC Neuroscience

ISSN: 1471-2202

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