Fig. 5From: Sodium formononetin-3'-sulphonate alleviates cerebral ischemia–reperfusion injury in rats via suppressing endoplasmic reticulum stress-mediated apoptosisSchematic diagram of the molecular mechanisms underlying the protective effects of Sul-F treatment against cerebral I/R injury. Sul-F treatment alleviated the I/R-induced activation of ER stress, thereby inhibiting multiple downstream pathways, including PERK/eIF2α/ATF4, IRE1/Caspase12/Caspase3 and CHOP/Bcl-2/Bax signal pathwayBack to article page