Fig. 6

Western blot analysis of COX-2 and iNOS expression in striatal tissue. COX-2 (a) and iNOS (b) expression levels were determined using Western blotting in the striatum. The ROT-administered group showed significant increase (*p < 0.05, 217.42 vs. 100 %) in the COX-2 level compared to the CONT group. NRD supplementation to the ROT-injected rats remarkably decreased the expression level of COX-2 (148.16 vs. 217.42 %) compared to the ROT group (c). Likewise, iNOS expression was also significantly increased (*p < 0.05, 206.35 vs. 100 %) in the ROT group compared to the CONT group. NRD treatment markedly decreased the iNOS expression (156.16 vs. 206.35 %) compared to the ROT group (d). NRD-only treatment decreased (89.9 vs. 100 %) COX-2 expression, while an increase (102.76 vs. 100 %) in iNOS expression was observed when compared to the CONT group (n = 3)