Figure 2

a Significant enrichment of genes regulated by transcription factors, c-Myc and CREB. Key: blue circles upregulation; red circles downregulation. Significant values for both enrichments were p-value = 1.62e−32, zScore 123.52 and gScore 123.52. b Enrichment of 18 of the 48 differentially-expressed mRNA transcripts which are either co-expressed or co-localized. Key: Myotrophin (Mtpn); B2RYX0_RAT, Naca; ROA3_RAT, Hnrnpa3; RGD1565095, Coa5; F1MAG5_RAT, Ret.