Skip to main content

Table 1 Administration of compounds in mice, in food intake Experiment 1 and 2

From: Synergistic effect of CART (cocaine- and amphetamine-regulated transcript) peptide and cholecystokinin on food intake regulation in lean mice

Experiment 1

      

Compound

Dose

i.p.

Time of application

Compound

Dose

i.c.v.

Time of application

No. animals

saline

 

-20 min

   

8

CCK-8

0.4 μg/kg

-20 min

   

6

 

4

-20 min

   

6

   

saline

 

-15 min

8

   

CART

0.1 μg/mouse

-15 min

6

    

0.5

-15 min

6

CCK-8

0.4 μg/kg

-20 min

CART

0.1 μg/mouse

-15 min

6

 

4

-20 min

 

0.1

-15 min

6

 

0.4 μg/kg

-20 min

 

0.5 μg/mouse

-15 min

6

 

4

-20 min

 

0.5

-15 min

7

Experiment 2

      

devazepide

1 mg/kg

-45 min

   

6

 

1

-45 min

CART

0.1 μg/mouse

-15 min

6

 

1

-45 min

 

0.5

-15 min

6

L365,260

1 mg/kg

-45 min

   

6

 

1

-45 min

 

0.5

-15 min

7

  1. At time = 0 min, mice were given weighed food pellets.