Volume 8 Supplement 2

Sixteenth Annual Computational Neuroscience Meeting: CNS*2007

Open Access

A population density framework that captures interneuronal correlations

BMC Neuroscience20078(Suppl 2):P25

DOI: 10.1186/1471-2202-8-S2-P25

Published: 6 July 2007

We have developed a population density framework that captures correlations between any pair of neurons in the population. We model each population of integrate-and-fire neurons as receiving input in the form of correlated Poisson processes. The evolution equation for the probability density of any pair of neurons within the population is a multivariate integro-differential equation which we solve numerically. We demonstrate the numerical method and compare the numerical solutions with Monte-Carlo simulations. Traditional population density approaches assume all neurons within a population are independent. However, correlations that are missed by these approaches can significantly alter network dynamics. Hence, the correlated population density method developed here could provide a framework to analyze how correlations propagate through networks and could be a computationally efficient method to accurately simulate large scale networks.

Authors’ Affiliations

Department of Mathematics, University of Minnesota


© Liu and Nykamp; licensee BioMed Central Ltd. 2007

This article is published under license to BioMed Central Ltd.