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Figure 2 | BMC Neuroscience

Figure 2

From: Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice

Figure 2

Changes in α4YFP nAChR expression in the medial habenula and the hippocampal medial perforant path. A) Montage of images of α4YFP nAChR expression in the medial perforant path and medial habenula (MHb) in a coronal mouse brain section. B) Chronic nicotine does not affect α4YFP nAChR expression in the MHb (14 ± 17% upregulation, p = 0.3, t-test). C) Chronic nicotine results in upregulation of α4YFP nAChRs in the medial perforant path (89 ± 16% upregulation, p = 0.001, Wilcoxon rank sum test) in mice.

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BMC Neuroscience

ISSN: 1471-2202

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