Figure 5

Dynamic activation and proliferation of Iba1+ cells after PT. A) Representative fluorescent images of Iba1 and Brdu double stained brain sections from mice at different times after PT. Right panels are the high resolution confocal images of boxed regions in the left panels. B) The density of Iba1+ cells in the penumbra. C-D) The density and cumulative density of Iba1+Brdu+ cells in the penumbra. E) The percentage of Iba1+Brdu+ double stained cells out of total Brdu+ cells in the penumbra. F) The percentage of Iba1+Brdu+ double stained cells out of total Iba1+ cells in the penumbra. In Figure (E-F), the cells were counted as in Figure 4. N=5 mice in each time point. *p<0.05, compared with value at day 4 after ischemia using ANOVA test.