Table 1 Mean ± S.D and independent t-test for HSP-70, GABA, serotonin, dopamine, oxytocin, and Interferon μ inducible protein 16 (IFI16) in neurointoxicated, Co Q protected and treated rat pups compared to healthy control

HSP70 (ng/ml)

Control

8

10.563 ± 0.370

PA

8

9.400 ± 0.490

0.001^a

CoQ-Protected group

6

10.050 ± 0.404

0.030^a

CoQ-treated group

8

10.033 ± 0.427

0.029^a

GABA (ng/10 mg)

Control

8

109.100 ± 4.666

PA

8

67.183 ± 3.125

0.001^a

CoQ-Protected group

6

95.417 ± 4.529

0.01^a

CoQ-treated group

8

85.079 ± 4.832

0.01^a

Serotonin (ng/ml)

Control

8

0.073 ± 0.017

PA

8

0.047 ± 0.011

0.004^a

CoQ-Protected group

6

0.095 ± 0.018

0.043^a

CoQ-treated group

8

0.097 ± 0.018

0.033^a

Dopamine (ng/ml)

Control

8

136.250 ± 18.468

PA

8

106.875 ± 12.229

0.002^a

CoQ-Protected group

6

169.167 ± 24.580

0.014^a

CoQ-treated group

8

160.000 ± 22.583

0.051^a

Oxytocin (Pg/ml)

Control

8

89.750 ± 4.464

PA

8

84.500 ± 4.751

0.039^a

CoQ-Protected group

6

95.667 ± 4.967

0.037^a

CoQ-treated group

8

95.000 ± 3.742

0.038^a

Interferon μ inducible protein 16 (Pg/ml)

Control

8

833.750 ± 63.906

PA

8

768.750 ± 53.033

0.044^a

CoQ-Protected group

6

931.667 ± 77.567

0.024^a

CoQ-treated group

8

983.333 ± 60.222

0.001^a