From: Microcirculatory, mitochondrial, and histological changes following cerebral ischemia in swine
Group | ||||
---|---|---|---|---|
Control (n = 6) | UCO (n = 3) | BCO (n = 4) | BCOH (n = 4) | |
Body weight (kg) | 19.5 ± 2.8 | 17.3 ± 2.3 | 22.8 ± 3.3 | 22.0 ± 3.4 |
HR (beats/min) | ||||
Before carotid ligation | 125 ± 15 | 112 ± 11 | 122 ± 21 | 112 ± 25 |
At brain biopsy | 111 ± 15 | 115 ± 9 | 103 ± 15 | 138 ± 16ab |
MAP (mmHg) | ||||
Before carotid ligation | 101 ± 14 | 92 ± 4 | 105 ± 6 | 99 ± 17 |
At brain biopsy | 94 ± 11 | 85 ± 9 | 89 ± 18 | 42 ± 7ab |
Arterial pH (mmHg) | ||||
Before carotid ligation | 7.50 ± 0.01 | 7.40 ± 0.01 | 7.53 ± 0.03 | 7.49 ± 0.06 |
At brain biopsy | 7.49 ± 0.02 | 7.52 ± 0.02 | 7.55 ± 0.04 | 7.39 ± 0.01ab |
Arterial pO2 (mmHg) | ||||
Before carotid ligation | 107.2 ± 27.1 | 116.0 ± 48.1 | 98.3 ± 30.1 | 76.8 ± 11.6 |
At brain biopsy | 100.0 ± 15.0 | 120.0 ± 50.5 | 82.7 ± 7.3 | 71.7 ± 9.8 |
Arterial pCO2 (mmHg) | ||||
Before carotid ligation | 38.8 ± 6.1 | 38.3 ± 7.6 | 41.0 ± 6.5 | 38.1 ± 6.3 |
At brain biopsy | 35.0 ± 8.0 | 37.0 ± 1.4 | 36.3 ± 4.6 | 41.3 ± 7.0 |
Esophageal temperature (ºC) | ||||
Before carotid ligation | 39.3 ± 1.0 | 39.5 ± 1.0 | 38.3 ± 0.6 | 38.6 ± 0.9 |
At brain biopsy | 39.4 ± 0.9 | 39.0 ± 1.2 | 38.0 ± 0.7 | 37.8 ± 0.7 |