Table 2 Effects of 10 μM CCh, 1 μM pirenzepine, or co-application of CCh and pirenzepine, as indicated, on the maximal amplitude of the field potentials, the maximal amplitude of EPSP (EPSP max ), the I 50 and slope factor of the EPSP input–output curve
Ctl (n = 9) | CCh (n = 9) | CCh + pir (n = 9) | |
|---|---|---|---|
Field max (mV) | −0.75 ± 0.25 | −0.29 ± 0.16 (*) | −0.69 ± 0.24 (+) |
EPSP max (mV) | 24.3 ± 1.5 | 20.6 ± 2 (*) | 23.6 ± 1.7 (+) |
I 50 (V) | 5.12 ± 0.81 | 9.23 ± 1.71 (*) | 6.22 ± 0.94 (*) (+) |
Slope factor | 1.61 ± 0.59 | 4.16 ± 0.95 (*) | 1.52 ± 0.40 (+) |
Ctl (n = 7) | pir (n = 7) | pir + CCh (n = 7) | |
Field max (mV) | −0.68 ± 0.3 | −0.7 ± 0.29 | −0.56 ± 0.25 (+) |
EPSP max (mV) | 20.5 ± 5.3 | 20.3 ± 5.1 | 16.0 ± 4 (*) (+) |
I 50 (V) | 8.41 ± 0.75 | 8.45 ± 0.76 | 9.37 ± 1.04 (*) |
Slope factor | 1.93 ± 0.54 | 2.18 ± 0.68 | 1.95 ± 0.31 |