Figure 6From: Dynamics of peptidergic secretory granule transport are regulated by neuronal stimulationSecretagogues differentially affect instantaneous velocity and direction. Instantaneous velocity and direction were calculated for tracked LDCVs in neurons kept under basal conditions or exposed to PMA or KCl for 5 min. LDCVs moving in the retrograde direction were assigned a negative sign, and those moving in the anterograde direction received a positive sign (A); the distribution of binned data is shown for representative cells from each treatment group. The fraction of LDCVs stopped or moving in a given direction (B) is plotted as an average; the relationship between direction and velocity was also analyzed (C). One-way ANOVA with Bonferroni post-test (SPSS package): *, p < 0.02; **, p < 0.01.Back to article page