Figure 7From: Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivinOpen field and fear conditioning defects in SurvivinCamcremice. (A) Open field test data are provided, with representative paths of control (wt) and SurvivinCamcre(ko) mice. (B) Contextual and auditory-cued fear conditioning in control and SurvivinCamcremice. Freezing times in pre-US, post-US and pre-CS trials were not different between control and SurvivinCamcremice. SurvivinCamcremice showed significantly less freezing responses as compared to controls during both the context and the auditory cue (CS) trials. US: unconditioned stimulus, shock; CS: conditioned stimulus, auditory cue. Results in panel B are reflected as means + SEM, n = 12 mice per group. **P < 0.001.Back to article page