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Table 2 List of significantly repressed genes affected by antidepressants

From: Gene expression profile analysis of genes in rat hippocampus from antidepressant treated rats using DNA microarray

Clone name (mRNA)

Fold change (log2mean)

Accession number

 

NS

Imip

Fluo

Phen

 

Immunoglobulin superfamily, member 6

-2.4 (1)

 

-2.2 (1)

-1.5 (1)

NM_133542

Secreted phosphoprotein 1

-2.3 (1)

 

-2.5 (1)

-2.2 (1)

NM_012881

Tumor necrosis factor alpha induced protein 6

-1.5 (7)

-1.6 (7)

-1.2 (7)

-1.0 (7)

XM_001065494

Leukocyte cell derived chemotaxin 1

-1.8 (1)

-1.3 (1)

  

NM_030854

Phospholipase A2, activating protein

 

-2.5 (1)

 

-1.6 (1)

NM_053866

Serum amyloid A 4

-1.5 (3)

 

-1.4 (3)

-1.3 (3)

NM_001009478

Mitogen-activated protein kinase 4

 

-1.1 (1)

  

XM_001053505

Tumor necrosis factor receptor superfamily, member 6

  

-1.8 (1)

-1.1 (1)

NM_139194

Angiopoietin 1

-3.8 (3)

 

-3.1 (3)

 

NM_053546

Apoptosis facilitator Bcl-2-like protein 14

-2.5 (3)

 

-1.0 (3)

-1.0 (3)

NM_001024338

Interferon gamma

-2.4 (3)

  

-1.0 (3)

NM_138880

Granzyme A

 

-2.0 (7)

-2.0 (7)

-1.2 (7)

NM_153468

  1. List of repressed genes affected less than 2 fold to their specific control by antidepressant treatments. ( ) indicated the sacrificed day of oral administered rat with antidepressant. NS; Nelumbinis Semen, Imip; imipramine, Fluo; fluoxetine, Phen; phenelzine