Figure 3

Systemic expression of Wld^S does not affect gross appearance or growth rates of mice. A - Photograph of 2 month old female mice from a representative litter produced by heterozygous Wld^Sbreeding pairs. This litter contains wild-type, heterozygous and homozygous Wld^Smice. There was no obvious gross difference in size, appearance or behaviour. B - Line graph showing body weight plotted against mouse age in days for wild-type (grey line) and Wld^S(black line) mice. No significant differences were observed between genotypes at any time-point examined (Anova). N = 7 wild-type, N = 5 Wld^S.