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  1. Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social ...

    Authors: Dhaksshaginy Rajalingam, Ingeborg Nymoen, Daniel Pitz Jacobsen, Mina Baarnes Eriksen, Erik Dissen, Morten Birkeland Nielsen, Ståle Valvatne Einarsen and Johannes Gjerstad

    Citation: BMC Neuroscience 2020 21:25

    Content type: Research article

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  2. Cerebral stroke occurs following ischemic and hemorrhagic lesions in the brain. Survival and recovery of stroke patients depend on the severity of the initial injury but also the therapeutic approaches applied...

    Authors: Ewen Tu, Qiong Chen, Li Tan and Yan Wang

    Citation: BMC Neuroscience 2020 21:24

    Content type: Research article

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  3. Alexithymia is a personality trait characterized by difficulties identifying and describing feelings, an externally oriented style of thinking, and a reduced inclination to imagination. Previous research has s...

    Authors: Nicole Rosenberg, Klas Ihme, Vladimir Lichev, Julia Sacher, Michael Rufer, Hans Jörgen Grabe, Harald Kugel, André Pampel, Jöran Lepsien, Anette Kersting, Arno Villringer and Thomas Suslow

    Citation: BMC Neuroscience 2020 21:23

    Content type: Research article

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  4. Polynitroxylated PEGylated hemoglobin (PNPH, aka SanFlow) possesses superoxide dismutase/catalase mimetic activities that may directly protect the brain from oxidative stress. Stabilization of PNPH with bound ...

    Authors: Soichiro Seno, Jun Wang, Suyi Cao, Manda Saraswati, Sharon Park, Jan Simoni, Li Ma, Bohdan Soltys, Carleton J. C. Hsia, Raymond C. Koehler and Courtney L. Robertson

    Citation: BMC Neuroscience 2020 21:22

    Content type: Research article

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  5. Transcranial direct current stimulation (tDCS) is a non-invasive brain modulation technique that has been proved to exert beneficial effects in the acute phase of stroke. To explore the underlying mechanism, w...

    Authors: Ke-Ying Zhang, Gang Rui, Jun-Ping Zhang, Ling Guo, Guang-Zhou An, Jia-Jin Lin, Wei He and Gui-Rong Ding

    Citation: BMC Neuroscience 2020 21:21

    Content type: Research article

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  6. Mental fatigue is usually caused by long-term cognitive activities, mainly manifested as drowsiness, difficulty in concentrating, decreased alertness, disordered thinking, slow reaction, lethargy, reduced work...

    Authors: Gang Li, Shan Huang, Wanxiu Xu, Weidong Jiao, Yonghua Jiang, Zhao Gao and Jianhua Zhang

    Citation: BMC Neuroscience 2020 21:20

    Content type: Research article

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  7. Empathy refers to the ability to recognise and share emotions with others. Several research groups have recognised observational fear in mice as a useful behavioural model for assessing their ability to empath...

    Authors: Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yu Takahashi, Yosuke Matsumoto, Motoi Okamoto and Takeshi Ishihara

    Citation: BMC Neuroscience 2020 21:19

    Content type: Research article

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  8. Neonatal hypoxic-ischemic encephalopathy (HIE) represents as a major cause of neonatal morbidity and mortality. However, the underlying molecular mechanisms in brain damage are still not fully elucidated. This...

    Authors: Ya Jiang, Xue Bai, Ting-Ting Li, Mohammed AL-Hawwas, Yuan Jin, Yu Zou, Yue Hu, Lin-Yi Liu, Ying Zhang, Qing Liu, Hao Yang, Jun Ma, Ting-Hua Wang, Jia Liu and Liu-Lin Xiong

    Citation: BMC Neuroscience 2020 21:18

    Content type: Research article

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  9. Vasomotor regulation of dermal blood vessels, which are critical in the function of the skin in thermoregulatory control, involves both neural and non-neural mechanisms. Whereas the role of sympathetic nerves ...

    Authors: Tao Zhang, Jiahui Niu, Yaxian Wang, Junying Yan, Wen Hu and Daguo Mi

    Citation: BMC Neuroscience 2020 21:15

    Content type: Research article

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  10. Patients positive for anti-glutamic acid decarboxylase 65 (GAD65) antibodies have attracted increasing attention. Their clinical manifestations are highly heterogeneous and can be comorbid with tumors. Current...

    Authors: Tao-Ran Li, Yu-Di Zhang, Qun Wang, Xiao-Qiu Shao, Zhi-Mei Li and Rui-Juan Lv

    Citation: BMC Neuroscience 2020 21:13

    Content type: Research article

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  11. Medium spiny neurons (MSNs) comprise the main body (95% in mouse) of the dorsal striatum neurons and represent dopaminoceptive GABAergic neurons. The cAMP (cyclic Adenosine MonoPhosphate)—mediated cascade of e...

    Authors: Vladimir N. Babenko, Anna G. Galyamina, Igor B. Rogozin, Dmitry A. Smagin and Natalia N. Kudryavtseva

    Citation: BMC Neuroscience 2020 21:12

    Content type: Research article

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  12. Pyridoxine (PDX; vitamin B6), is an essential vitamin. PDX deficiency induces various symptoms, and when PDX is misused it acts as a neurotoxicant, inducing severe sensory neuropathy.

    Authors: Sumin Yun, Woosuk Kim, Min Soo Kang, Tae Hyeong Kim, Yoonhwan Kim, Jin-Ok Ahn, Jung Hoon Choi, In Koo Hwang and Jin-Young Chung

    Citation: BMC Neuroscience 2020 21:11

    Content type: Research article

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  13. Following the publication of this article [1], it has been noted by the authors that an image of the same cell nuclei has been used in error twice, in Fig. 8, parts A and B. These images are redundant in this ...

    Authors: Claudie Hooper, Ricardo Sainz-Fuertes, Steven Lynham, Abdul Hye, Richard Killick, Alice Warley, Cecilia Bolondi, Jennifer Pocock and Simon Lovestone

    Citation: BMC Neuroscience 2020 21:10

    Content type: Correction

    Published on:

    The original article was published in BMC Neuroscience 2012 13:144

  14. Neuromyelitis optica (NMO) is a demyelinating disease primarily affecting the optic nerves and spinal cord. It is distinguished from other demyelinating conditions by the presence of AQP4-IgG and serum aquapor...

    Authors: Etedal Ahmed AbuElbasher Ibrahim, Fatima Gammer and Alsadig Gassoum

    Citation: BMC Neuroscience 2020 21:9

    Content type: Research article

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  15. There has been much discussion recently about the occurrence of neuropsychological complications during the perioperative period. Diabetes is known to be one of the metabolic risk factors. Although the number ...

    Authors: Momoka Nishimura, Yuki Nomura, Moritoki Egi, Norihiko Obata, Makoto Tsunoda and Satoshi Mizobuchi

    Citation: BMC Neuroscience 2020 21:8

    Content type: Research article

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  16. It is a crucial task of brain science researches to explore functional connective maps of Biological Neural Networks (BNN). The maps help to deeply study the dominant relationship between the structures of the...

    Authors: Mei-jia Zhu, Chao-yi Dong, Xiao-yan Chen, Jing-wen Ren and Xiao-yi Zhao

    Citation: BMC Neuroscience 2020 21:7

    Content type: Methodology article

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  17. Synaptic degeneration and accumulation of amyloid β-peptides (Aβ) are hallmarks of the Alzheimer diseased brain. Aβ is synaptotoxic and produced by sequential cleavage of the amyloid precursor protein (APP) by...

    Authors: Jolanta L. Lundgren, Lina Vandermeulen, Anna Sandebring-Matton, Saheeb Ahmed, Bengt Winblad, Monica Di Luca, Lars O. Tjernberg, Elena Marcello and Susanne Frykman

    Citation: BMC Neuroscience 2020 21:6

    Content type: Research article

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  18. Opioids are the most effective drugs commonly prescribed to treat pain. Due to their addictive nature, opioid pain relievers are now second to marijuana, ahead of cocaine with respect to dependence. Ours and o...

    Authors: Ruping Fan, Lisa M. Schrott, Stephen Snelling, John Felty, Derrel Graham, Patrick L. McGauly, Thomas Arnold and Nadejda L. Korneeva

    Citation: BMC Neuroscience 2020 21:4

    Content type: Research article

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  19. It is difficult to set up a balanced higher-order full-factorial experiment that can capture multiple intricate interactions between cognitive and psycholinguistic factors underlying bilingual speech productio...

    Authors: Severin Schramm, Noriko Tanigawa, Lorena Tussis, Bernhard Meyer, Nico Sollmann and Sandro M. Krieg

    Citation: BMC Neuroscience 2020 21:3

    Content type: Research article

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  20. The growing abuse of amphetamine-type stimulants leads to new challenges to human health. A possible addiction mechanism has been proposed by altered functional architecture of the nucleus accumbens (NAc) duri...

    Authors: Yun Wang, Kai-Juan Yan, Chen-Xiao Fan, Xiao-Nian Luo and Yuan Zhou

    Citation: BMC Neuroscience 2019 20:66

    Content type: Research article

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  21. Histone deacetylase-3 (HDAC3) promotes neurodegeneration in various cell culture and in vivo models of neurodegeneration but the mechanism by which HDAC3 exerts neurotoxicity is not known. HDAC3 is known to be...

    Authors: Anto Sam Crosslee Louis Sam Titus, Dharmendra Sharma, Min Soo Kim and Santosh R. D’Mello

    Citation: BMC Neuroscience 2019 20:65

    Content type: Research article

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  22. Infection is an important clinical complication facing stroke-patients and triples the risk of death within 30 days post-stroke via mechanisms which are poorly understood.

    Authors: Ping Wang, Jiaqi Zhang, Feifei Guo, Shuang Wang, Yi Zhang, Defeng Li, Haiyu Xu and Hongjun Yang

    Citation: BMC Neuroscience 2019 20:64

    Content type: Research article

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  23. Sodium ion transportation plays a crucial role in the pathogenesis of hypoxic–ischemic brain injury. Amiodarone, a Vaughan-Williams class III antiarrhythmic drug, has been widely used to treat life-threatening...

    Authors: Masakazu Kotoda, Sohei Hishiyama, Tadahiko Ishiyama, Kazuha Mitsui and Takashi Matsukawa

    Citation: BMC Neuroscience 2019 20:62

    Content type: Research article

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  24. Parkinson’s disease (PD) is characterised by dopaminergic cell loss within the substantia nigra pars compacta (SNc) that leads to reduced striatal dopamine content and resulting motor deficits. Identifying new...

    Authors: Edward J. R. Fletcher, Lawrence D. F. Moon and Susan Duty

    Citation: BMC Neuroscience 2019 20:61

    Content type: Research article

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  25. Ketamine has been reported to cause neonatal neurotoxicity in a variety of developing animal models. Various studies have been conducted to study the mechanism of neurotoxicity for general anesthetic use durin...

    Authors: Zhanqiang Zhao, Bing Li, Yuqing Wu, Xujun Chen, Yan Guo, Yang Shen and He Huang

    Citation: BMC Neuroscience 2019 20:60

    Content type: Research article

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  26. The aim was to examine the impact of lipopolysaccharide-induced systemic inflammation on expression of mRNA for cocaine- and amphetamine-regulated transcript (CART) and the thyrotropin receptor (TSHR) and its ...

    Authors: Jonathan R. Burgos, Britt-Marie Iresjö, Linda Olsson and Ulrika Smedh

    Citation: BMC Neuroscience 2019 20:59

    Content type: Research article

    Published on:

  27. The pharmacodynamic results of diazepam and ethanol administration are similar, in that each can mediate amnestic and sedative-hypnotic effects. Although each of these molecules effectively reduce the activity...

    Authors: Matthias Kreuzer, Paul S. García, Verena Brucklacher-Waldert, Rebecca Claassen, Gerhard Schneider, Bernd Antkowiak and Berthold Drexler

    Citation: BMC Neuroscience 2019 20:58

    Content type: Research article

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  28. Mammalian Shc (Src homology and collagen) proteins comprise a family of four phosphotyrosine adaptor molecules which exhibit varied spatiotemporal expression and signaling functions. ShcD is the most recently ...

    Authors: Hannah N. Robeson, Hayley R. Lau, Laura A. New, Jasmin Lalonde, John N. Armstrong and Nina Jones

    Citation: BMC Neuroscience 2019 20:57

    Content type: Research article

    Published on:

  29. Non-motor symptoms are common aspects of Parkinson’s disease (PD) occurring even at the prodromal stage of the disease and greatly affecting the quality of life. Here, we investigated whether non-motor symptom...

    Authors: Flavia Niccolini, Heather Wilson, Beniamino Giordano, Konstantinos Diamantopoulos, Gennaro Pagano, Kallol Ray Chaudhuri and Marios Politis

    Citation: BMC Neuroscience 2019 20:55

    Content type: Research article

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  30. The pathogenesis of medication overuse headache (MOH) involves hyperexcitability of cortical and trigeminal neurons. Derangement of the brainstem modulating system, especially raphe nuclei may contribute to th...

    Authors: Prangtip Potewiratnanond, Supang Maneesri le Grand, Anan Srikiatkhachorn and Weera Supronsinchai

    Citation: BMC Neuroscience 2019 20:54

    Content type: Research article

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  31. Neuroactive steroids seem to be implicated in a variety of neurophysiological and behavioral processes, such as sleep, learning, memory, stress, feeding and aging. Numerous studies have also addressed this imp...

    Authors: Jan Martin, Eva Plank, Bettina Jungwirth, Alexander Hapfelmeier, Armin Podtschaske and Simone M. Kagerbauer

    Citation: BMC Neuroscience 2019 20:53

    Content type: Research article

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  32. Neurological complications may occur in patients with acute or chronic renal failure; however, in cases of acute renal failure, the signs and symptoms are usually more pronounced, and progressed rapidly. Oxida...

    Authors: Fatemeh Sharifi, Parham Reisi and Maryam Malek

    Citation: BMC Neuroscience 2019 20:52

    Content type: Research article

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  33. We aimed to study the role of amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor (AMPAR) glutamate receptor 2 (GluR2) subunit trafficking, and activity changes in short-term neuroprotection provided b...

    Authors: Chenxu Wang, Ying Wei, Yuan Yuan, Yonghao Yu, Keliang Xie, Beibei Dong, Yuan Shi and Guolin Wang

    Citation: BMC Neuroscience 2019 20:51

    Content type: Research article

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  34. Movement performance depends on the synaptic interactions generated by coherent parallel sensorimotor cortical outputs to different downstream targets. The major outputs of the neocortex to subcortical structu...

    Authors: Rafael Olivares-Moreno, Mónica López-Hidalgo, Alain Altamirano-Espinoza, Adriana González-Gallardo, Anaid Antaramian, Verónica Lopez-Virgen and Gerardo Rojas-Piloni

    Citation: BMC Neuroscience 2019 20:50

    Content type: Research article

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  35. In animal research, authorities require a classification of anticipated pain levels and a perioperative analgesia protocol prior to approval of the experiments. However, data on this topic is rare and so is th...

    Authors: Irina Staib-Lasarzik, Nadine Nagel, Anne Sebastiani, Eva-Verena Griemert and Serge C. Thal

    Citation: BMC Neuroscience 2019 20:49

    Content type: Research article

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  36. Electrical stimulation is widely used in experimental pain research but it lacks selectivity towards small nociceptive fibers. When using standard surface patch electrodes and rectangular pulses, large fibers ...

    Authors: Rosa Hugosdottir, Carsten Dahl Mørch, Ole Kæseler Andersen, Thordur Helgason and Lars Arendt-Nielsen

    Citation: BMC Neuroscience 2019 20:48

    Content type: Research article

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  37. There is a need for new approaches to increase the knowledge of the membrane excitability of small nerve fibers both in healthy subjects, as well as during pathological conditions. Our research group has previ...

    Authors: Rosa Hugosdottir, Carsten Dahl Mørch, Cecilia Klitgaard Jørgensen, Camilla Winther Nielsen, Mathias Vassard Olsen, Mads Jozwiak Pedersen and Jenny Tigerholm

    Citation: BMC Neuroscience 2019 20:47

    Content type: Research article

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  38. The Pde6brd1 (Rd1) mouse is widely used as a murine model for human retinitis pigmentosa. Understanding the spatio-temporal patterns of cone degeneration is important for evaluating potential treatments. In th...

    Authors: Daniel S. Narayan, Jack Ao, John P. M. Wood, Robert J. Casson and Glyn Chidlow

    Citation: BMC Neuroscience 2019 20:46

    Content type: Research article

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  39. Systemic inflammation is an important risk factor for neurodevelopmental impairments in preterm infants. Premyelinating oligodendrocytes are main building blocks of white matter in preterm infants and vulnerab...

    Authors: Seung Han Shin, Ee-Kyung Kim, Kyung-yup Lee and Han-Suk Kim

    Citation: BMC Neuroscience 2019 20:45

    Content type: Research article

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  40. Traumatic brain injury (TBI) is a widespread public health problem and a signature injury of our military in modern conflicts. Despite the long-term effects of even mild brain injuries, an effective treatment ...

    Authors: Whitney A. Ratliff, Jessica N. Saykally, Ronald F. Mervis, Xiaoyang Lin, Chuanhai Cao and Bruce A. Citron

    Citation: BMC Neuroscience 2019 20:44

    Content type: Research article

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  41. The aim of the present study was to evaluate the stability of brain arousal in adult attention-deficit/hyperactivity disorder (ADHD) outpatients with and without depressive symptomatology, and its association ...

    Authors: Jue Huang, Christine Ulke and Maria Strauss

    Citation: BMC Neuroscience 2019 20:43

    Content type: Research article

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  42. Parkinson's disease is a progressive degenerative nervous system disease. Recent studies have shown that secondary changes in the GABA system play directly affect the pathogenesis of PD. There is still much de...

    Authors: Lixuan Huang, Yande Ren, Zisan Zeng, Hao Ren, Shaojun Li, Shengnan He, Fan He and Xiangrong Li

    Citation: BMC Neuroscience 2019 20:42

    Content type: Research article

    Published on:

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