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Techniques in Neuroscience

This section covers techniques for fundamental and clinical neurosciences, including, but are not limited to, neural signal processing, neuroimaging, neural interfaces, neuromodulation and brain stimulation.

  1. Rodent brain slices—particularly hippocampal slices—are widely used in experimental investigations of epileptiform activity. Oxygenated artificial cerebrospinal fluid (ACSF) is used to maintain slices in vitro...

    Authors: Haiyu Liu, Sai Zhang and Liang Zhang

    Citation: BMC Neuroscience 2021 22:46

    Content type: Methodology article

    Published on:

  2. A common problem in neurophysiological signal processing is the extraction of meaningful information from high dimension, low sample size data (HDLSS). We present RoLDSIS (regression on low-dimension spanned i...

    Authors: Adrielle C. Santana, Adriano V. Barbosa, Hani C. Yehia and Rafael Laboissière

    Citation: BMC Neuroscience 2021 22:1

    Content type: Methodology article

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  3. Conditioned pain modulation (CPM) evaluates the effect of a painful conditioning stimulus (CS) on a painful test stimulus (TS). Using painful cutaneous electrical stimulation (PCES) as TS and painful cold wate...

    Authors: A. T. L. Do, E. K. Enax-Krumova, Ö. Özgül, L. B. Eitner, S. Heba, M. Tegenthoff, C. Maier and O. Höffken

    Citation: BMC Neuroscience 2020 21:53

    Content type: Research article

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  4. To identify mechanisms of cortical plasticity of the visual cortex and to quantify their significance, sensitive parameters are warranted. In this context, multifocal visual evoked potentials (mfVEPs) can make...

    Authors: Robert Kolbe, Aykut Aytulun, Ann-Kristin Müller, Marius Ringelstein, Orhan Aktas, Alfons Schnitzler, Hans-Peter Hartung, Stefan Jun Groiss and Philipp Albrecht

    Citation: BMC Neuroscience 2020 21:48

    Content type: Research article

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  5. The inter-scanner reproducibility of brain volumetry is important in multi-site neuroimaging studies, where the reliability of automated brain segmentation (ABS) tools plays an important role. This study aimed...

    Authors: Sirui Liu, Bo Hou, Yiwei Zhang, Tianye Lin, Xiaoyuan Fan, Hui You and Feng Feng

    Citation: BMC Neuroscience 2020 21:35

    Content type: Research article

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  1. In this study, nonlinear based time–frequency (TF) and time domain investigations are employed for the analysis of electroencephalogram (EEG) signals of mild cognitive impairment–Alzheimer’s disease (MCI–AD) p...

    Authors: T. Nimmy John, Puthankattil Subha Dharmapalan and N. Ramshekhar Menon

    Citation: BMC Neuroscience 2019 20:38

    Content type: Research article

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  2. Transcranial focused ultrasound (tFUS) attracts wide attention in neuroscience as an effective noninvasive approach to modulate brain circuits. In spite of this, the effects of tFUS on the brain is still uncle...

    Authors: Evgenii Kim, Eloise Anguluan, Sangyeon Youn, Jihun Kim, Jae Youn Hwang and Jae Gwan Kim

    Citation: BMC Neuroscience 2019 20:12

    Content type: Research article

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  3. Transcranial ultrasonic stimulation is a novel noninvasive tool for neuromodulation, and has high spatial resolution and deep penetration. Although it can increase excitation of neurons, its effects on neuron ...

    Authors: Kun Cui, Shuai Zhang, Jinyao Sun, Xueying Zhang, Chong Ding and Guizhi Xu

    Citation: BMC Neuroscience 2019 20:3

    Content type: Research article

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  4. Low-intensity pulsed ultrasound stimulation (LIPUS) has been proven to be a noninvasive method with high spatial resolution and deep penetration. Previous studies have qualitatively demonstrated that the elect...

    Authors: Yi Yuan, Xingran Wang, Jiaqing Yan and Xiaoli Li

    Citation: BMC Neuroscience 2018 19:78

    Content type: Research article

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  5. Tinnitus is the perception of sound in the absence of any external acoustic stimulation. Transcranial direct current stimulation (tDCS) has shown promising though heterogeneous therapeutic outcomes for tinnitu...

    Authors: Tifei Yuan, Ali Yadollahpour, Julio Salgado-Ramírez, Daniel Robles-Camarillo and Rocío Ortega-Palacios

    Citation: BMC Neuroscience 2018 19:66

    Content type: Research article

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  6. Pulsed transcranial ultrasound stimulation (pTUS) can modulate the neuronal activity of motor cortex and elicit muscle contractions. Cortico-muscular coupling (CMC) can serve as a tool to identify interaction ...

    Authors: Ping Xie, Sa Zhou, Xingran Wang, Yibo Wang and Yi Yuan

    Citation: BMC Neuroscience 2018 19:60

    Content type: Research article

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  7. Low-intensity transcranial focused ultrasound (tFUS) has emerged as a new non-invasive modality of brain stimulation with the potential for high spatial selectivity and penetration depth. Anesthesia is typical...

    Authors: Wonhye Lee, Phillip Croce, Ryan W. Margolin, Amanda Cammalleri, Kyungho Yoon and Seung-Schik Yoo

    Citation: BMC Neuroscience 2018 19:57

    Content type: Research article

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  9. The brain is continuously targeted by a wealth of stimuli with complex spatio-temporal patterns and has presumably evolved in order to cope with those inputs in an optimal way. Previous studies investigating t...

    Authors: Francesca Scarsi, Jacopo Tessadori, Michela Chiappalone and Valentina Pasquale

    Citation: BMC Neuroscience 2017 18:49

    Content type: Research article

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  10. Previous neuroimaging studies have shown the hemodynamic effect of either preconditioning or postconditioning anesthesia in ischemic stroke model. However, the anesthetic effect in hemodynamics during and imm...

    Authors: Hongyang Lu, Yao Li, Bin Bo, Lu Yuan, Xiaodan Lu, Hangdao Li and Shanbao Tong

    Citation: BMC Neuroscience 2017 18:10

    Content type: Research article

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  11. The spatial resolution of repetitive navigated transcranial magnetic stimulation (rTMS) for language mapping is largely unknown. Thus, to determine a minimum spatial resolution of rTMS for language mapping, we...

    Authors: Nico Sollmann, Theresa Hauck, Lorena Tussis, Sebastian Ille, Stefanie Maurer, Tobias Boeckh-Behrens, Florian Ringel, Bernhard Meyer and Sandro M. Krieg

    Citation: BMC Neuroscience 2016 17:67

    Content type: Research article

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  12. Rehabilitation, which is essential for amputees with myoelectric hands, can improve the quality of daily life by remodeling the neuron network. In our study, we aim to develop a cerebral blood perfusion (CBF) ...

    Authors: Qiufang Liu, Xiujuan Zheng, Panli Li, Lian Xu, Longwen He, Zhao Mei, Yinyan Zhu, Gang Huang, Chunlong Zhong and Shaoli Song

    Citation: BMC Neuroscience 2016 17:59

    Content type: Research article

    Published on:

BMC Neuroscience

ISSN: 1471-2202

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