Topics of interest include, but are not limited to, neuroinflammation, neurodegenerative pathophysiology, neurodevelopmental disorders, neuropsychiatric disorders, addiction, stroke, ischemia, spinal cord injury, traumatic brain injury (TBI), demyelination and genetic and genomic analysis of diseases of the nervous system.
Glutamate carboxypeptidase II gene knockout attenuates oxidative stress and cortical apoptosis after traumatic brain injury
Glutamate carboxypeptidase II (GCPII) inactivates the peptide co-transmitter N-acetylaspartylglutamate following synaptic release. Inhibition of GCPII elevates extracellular levels of the peptide, inhibits glutam...
Citation: BMC Neuroscience 2016 17:15