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Fig. 6 | BMC Neuroscience

Fig. 6

From: Protective effect of resveratrol on mitochondrial biogenesis during hyperoxia-induced brain injury in neonatal pups

Fig. 6

Illustration of how Res reduces hyperoxic brain injury through the PGC-1α/Nrf/TFAM/mtDNA signalling pathway. Res: resveratrol; Sirt1, silencing information regulator 2-related enzyme 1; PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1α; Nrf1, nuclear respiratory factor 1; Nrf2, nuclear respiratory factor 2; Keap1, Kelch-like ECH associated protein 1; TFAM, mitochondrial transcription factor A; mtDNA, mitochondrial DNA.

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BMC Neuroscience

ISSN: 1471-2202

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