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Fig. 2 | BMC Neuroscience

Fig. 2

From: Cudraflavone B induces human glioblastoma cells apoptosis via ER stress-induced autophagy

Fig. 2

CUB activates ER stress. a, b Gene Ontology (GO) pathways a and Kyoto Encyclopedia of Genes and Genomes (KEGG) b analyzed the transcriptome sequencing of U87 GBM cells after CUB treatment. U87 cells were treated with 10 μM of CUB. c Quantitative real-time PCR (qPCR) analysis of GBM cells treated with of CUB (5,10, 20 µM) for 24 h. d Immunoblotting of the ER stress markers, p-eIF2Α and CHOP, in GBM cells (Notion: here are cropped blots, original cropped images and replicates are presented in Additional file 1: Fig. S2). e Fluorescence images of ATF4 in GBM cells exposed to CUB (10 μM) or control for 24 h. Data were mean ± SEM from three independent experiments. The statistical analysis was performed using one-way ANOVA, and the significance labeled as * P < 0.05, ** P < 0.01 and *** P < 0.001

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