Fig. 4
From: Cytokine expression profiles in white blood cells of patients with small fiber neuropathy
Relative gene expression of cytokines in SFN patients stratified for pain phenotype. The scatter plots show the gene expression of pro- and anti-inflammatory cytokines when comparing patients with moderate (NRS < 4) to severe (NRS ≥ 4) pain a and with acral pain to generalized pain (b); Gene expression was higher of IL-2 in patients with moderate pain compared to severe pain (a) and of IL-10 in patients with acral pain compared to generalized pain (b). Numbers of samples investigated: moderate pain = 35; severe pain = 17; acral pain = 15; generalized pain = 21. IL− interleukin, NRS numeric rating scale, SFN small fiber neuropathy, TGF transforming growth factor beta-1, TNF tumor necrosis factor-alpha. *p < 0.05; **p < 0.01