Fig. 1

The effects of Sul-F treatment on infarct volume, neurological score and pathological changes of I/R injured brains. A Infarct volume was determined with TTC staining. The white area defined the infarct area (n = 6). B The infarct volume was expressed as the ratio of (infarct volume / the whole brain volume) × 100% (n = 6). C Neurological score (n = 15). The neurological function of the rats after 24 h of reperfusion was evaluated according to the Zea-Longa score standard. The higher the score, the more severe the neurological impairment is. Neurological score data was presented as M (P₂₅ ~ P₇₅). ^**P < 0.01 compared with the Sham group, ^△△P < 0.01 compared with the MCAO group. Data were presented as mean ± SEM from at least three independent experiments. ^**P < 0.01 compared with Sham group, ^△P < 0.05 and ^△△P < 0.01 compared with the MCAO group. D Histopathological characteristics (n = 6). After 24 h reperfusion, the ischemic penumbra area of brain tissue was stained with HE, which was observed at 100 × and 400 × , respectively. Scale bar = 100 μm