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Table 1 Scoring of H&E stained burn injured hind paws

From: Exploring combat stress exposure effects on burn pain in a female rodent model

Epidermis

 0

Normal

 1

Epidermal degeneration

 2

Epidermal ulceration

 3

Epidermal hyperplasia

Granulation tissue/Fibroplasia

 0

None

 1

GT > Fibroplasia

 2

GT = Fibroplasia

 3

GT < Fibroplasia

Skeletal myocyte degeneration, necrosis, atrophy, loss

 0

Normal

 1

 < 25% (% of total skeletal muscle)

 2

26–50% (% of total skeletal muscle)

 3

51–75% (% of total skeletal muscle)

 4

 > 75% (% of total skeletal muscle)

Superficial bacteria

 0

Absent

 1

Present

Inflammation

(neutrophils/histiocytes/lymphocytes and plasma cells)

 0

None

 1

Mild number of inflammatory cells

 2

Moderate number of inflammatory cells

 3

Marked number of inflammatory cells

New bone growth (digit)

 0

None

 1

Mild

 2

Moderate

 3

Marked

 4

Severe

  1. Slides were examined and scored by a board certified veterinary pathologist utilizing the scoring system detailed in Table 1