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Fig. 2 | BMC Neuroscience

Fig. 2

From: Albumin alleviated esketamine-induced neuronal apoptosis of rat retina through downregulation of Zn2+-dependent matrix metalloproteinase 9 during the early development

Fig. 2

Increasing neurons in retinal GCL colocalized with MMP9 after esketamine exposure. A Representative images show immunostaining for MMP9 (red) and NeuN (green) in GCL with and without esketamine exposure. The arrowheads in white indicate ganglion cells (marked by NeuN) colocalized with MMP9. Scale bar, 50 μm. B The colocalization image is magnified. Scale bar, 20 μm. C Bar graph and D Venn diagram quantify the increase in overlap (neurons colocalized with MMP9 in GCL) from 4% in control to 17% after esketamine exposure (n = 4 retinas per group). E Representative images show immunostaining for MMP9 (red) and Iba1 (green) in GCL. Scale bar, 50 μm

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BMC Neuroscience

ISSN: 1471-2202

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