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Table 3 Performances of ADC in the comparison of tumor grading and genotypes

From: Feasibility of evaluating the histologic and genetic subtypes of WHO grade II-IV gliomas by diffusion-weighted imaging

 

Low grade vs High grade

IDH-mut vs IDH-wt

MGMT-m vs MGMT-um

TERT-mut vs TERT-wt

nADC

 AUC

0.787

0.836

0.651

0.607

 95% CI

0.701–0.874

0.757–0.914

0.546–0.757

0.494–0.721

 Cutoff value

1.56

1.60

1.59

1.89

 Sensitivity

83.8%

82.2%

59.1%

31.0%

 Specificity

68.9%

80.0%

73.8%

90.9%

omADC

 AUC

0.750

0.777

NA

0.617

 95% CI

0.656–0.844

0.688–0.865

0.503–0.730

 Cutoff value

0.0012

0.0012

0.0012

 Sensitivity

78.4%

88.4%

73.3%

 Specificity

71.6%

67.7%

50.9%

  1. CI confidence interval; Sen sensitivity; Sep specificity; NA not available