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Fig. 5 | BMC Neuroscience

Fig. 5

From: Mechanism of LSD1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the miR-21-5p/NLRP12 axis

Fig. 5

miR-21-5p targets and binds to NLRP12 to downregulate NLRP12. A-B: The binding of miR-21-5p to NLRP12 was detected via RNA pull-down and dual-luciferase assays; C-D: The expression levels of NLRP12 were examined via RT-qPCR and Western blot analysis. Each cell experiment was performed in triplicate; measurement data were presented as mean ± standard deviation (SD); data in panel A were analyzed via the t-test; data in panels C and D were analyzed via one-way ANOVA and data in panel B were analyzed via two-way ANOVA, followed by Tukey’s multiple comparison test; *p < 0.05

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