Fig. 7
From: Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury
Quantification of microglia/macrophages expressing CD86 (M1 marker) and KOR. Morphine significantly increases the number of CD86+ macrophages (C) in contused rats after 3 days of administration but had no effect on CD86+ microglia at any timepoint (A). However, 3 days of morphine administration significantly increased the number of CD86 + microglia and macrophages expressing KORs (B and D). Results shown as Mean ± S.E.M. *p < 0.05, n = 5–6