Fig. 5
From: Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury
Effects of morphine on thermal and tactile recovery. Morphine produced robust analgesia on thermal (A) and tactile (B, C) reactivity. There was no reduction in the efficacy of morphine across days on either sensory test. Conversely, the development of hyperalgesia was observed by day 7 on the tactile reactivity (E, F) test but not for thermal reactivity (D). Contused rats treated with morphine displayed significantly lower thresholds for vocal (F), and a trend for reduction of motor (E), responses on the tactile reactivity test. Results shown as Mean ± S.E.M. *p < 0.05, n = 10